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埃塞俄比亚达巴特地区涂阳肺结核聚集性:一项基于人群的横断面研究。

The clustering of smear-positive tuberculosis in Dabat, Ethiopia: a population based cross sectional study.

机构信息

Institute of Public Health, the University of Gondar, Gondar, Ethiopia.

出版信息

PLoS One. 2013 May 23;8(5):e65022. doi: 10.1371/journal.pone.0065022. Print 2013.

Abstract

BACKGROUND

In Ethiopia where tuberculosis epidemic remains high, studies that describe hotspots of the disease are unavailable. This study tried to detect the spatial distribution and clustering of smear-positive tuberculosis cases in Dabat, Ethiopia.

METHODS AND FINDINGS

A population-based cross sectional study conducted in the Dabat Health and Demographic Surveillance System site from October 2010 to September 2011 identified smear-positive tuberculosis cases. Trained field workers collected demographic and location data from each study participant through house-to-house visits. A spatial scan statistic was used to identify purely spatial and space-time clusters of tuberculosis among permanent residents. Two significant (p<0.001) spatial and space-time clusters were identified in the study district.

CONCLUSION

Tuberculosis is concentrated in certain geographic locations in Dabat, Ethiopia. This kind of clustering can be common in the country, so the National Tuberculosis Control Program can be more effective by identifying such clusters and targeting interventions.

摘要

背景

在结核病流行仍然很高的埃塞俄比亚,尚未有描述该疾病热点的研究。本研究试图在埃塞俄比亚的达巴特(Dabat)检测涂阳肺结核病例的空间分布和聚集情况。

方法和发现

2010 年 10 月至 2011 年 9 月在达巴特健康和人口监测系统进行了一项基于人群的横断面研究,以确定涂阳肺结核病例。经过培训的现场工作人员通过挨家挨户走访,从每位研究参与者那里收集人口统计学和位置数据。空间扫描统计用于识别常住居民中结核病的纯空间和时空聚集。在研究地区确定了两个显著的(p<0.001)空间和时空聚集。

结论

结核病在埃塞俄比亚的达巴特集中在某些特定的地理位置。这种聚集在该国可能很常见,因此,通过识别这些聚集并针对干预措施,国家结核病控制规划可以更有效。

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