Malyschew J I, Fokin A A, Sotow S P, Werbowetzki L P
Abteilung für Gefässchirurgie, Medizinischen Hochschule, Tscheljabinsk, UdSSR.
Vasa. 1990;19(2):138-41.
This is a report on 153 patients (from 22 to 86 years of age) with acute ischemic gangrene of the lower limbs and severe concomitant diseases (ischemic heart disease, arterial hypertension, diabetes mellitus, etc.). Freezing of the necrotic limb with application of a tourniquet and general medical treatment were performed previous to amputation. Freezing was accomplished by dry ice and common ice in 16 patients and by a special refrigerator in 137 patients. 17 patients in a very grave condition died during refrigeration. Amputation of the lower limb was performed in 136 patients, 110 of them tolerated the operation favourably. Complications of wound-healing were observed in 23.1%.
这是一份关于153例患者（年龄在22至86岁之间）的报告，这些患者患有下肢急性缺血性坏疽并伴有严重的伴随疾病（缺血性心脏病、动脉高血压、糖尿病等）。在截肢前，对坏死肢体进行了扎止血带冷冻及一般药物治疗。16例患者通过干冰和普通冰块进行冷冻，137例患者通过特殊冰箱进行冷冻。17例病情极其严重的患者在冷冻期间死亡。136例患者进行了下肢截肢手术，其中110例手术耐受良好。观察到伤口愈合并发症的发生率为23.1%。
