Eickerling B, Rakus H, Martin M
Geriatrische Klinik, Städtischen Kliniken Duisburg.
Vasa. 1990;19(2):142-8.
The present study deals with long-term results in patients in whom deep venous occlusions were removed by fibrinolytic treatment. For this an ultrahigh streptokinase regimen was used. The average follow-up period was 18.9 +/- 6.7 months. The number of patients investigated was 27. In the group of femoral veins formerly cleared by fibrinolysis 2 of 21 (9.5%) were recorded as reoccluded. An unexpected removal of a femoral thrombosis still in existence immediately after fibrinolytic therapy was seen in one patient and evaluated as a late lytic event. In the group of iliac vein thrombosis cleared by fibrinolytic treatment no reocclusions occurred. In conclusion it can be said that the reocclusion-tendency of veins cleared by fibrinolysis is relatively low. This finding constitutes a special incentive for fibrinolytic treatment of deep vein thrombosis.
本研究涉及通过纤维蛋白溶解疗法清除深静脉闭塞的患者的长期结果。为此采用了超高剂量链激酶方案。平均随访期为18.9±6.7个月。调查的患者数量为27例。在先前通过纤维蛋白溶解清除的股静脉组中，21例中有2例（9.5%）被记录为再次闭塞。在1例患者中观察到在纤维蛋白溶解治疗后立即意外清除了仍然存在的股静脉血栓形成，并被评估为晚期溶解事件。在通过纤维蛋白溶解治疗清除的髂静脉血栓形成组中未发生再次闭塞。总之，可以说通过纤维蛋白溶解清除的静脉的再闭塞倾向相对较低。这一发现为深静脉血栓形成的纤维蛋白溶解治疗提供了特殊的动力。
