Suojaranta-Ylinen R, Hendolin H, Alhava E, Kontra K
Department of Anaesthesia, Kuopio University Central Hospital, Finland.
Agents Actions. 1990 Apr;30(1-2):297-9. doi: 10.1007/BF01969066.
The effects of famotidine (40 mg), ranitidine (300 mg) and sodium citrate (30 ml) on the gastric pH and volume were tested in 114 patients undergoing upper abdominal surgery. Gastric content was aspirated through a multiorifice tube immediately after intubation, at the end of operation and after a recovery room period of one hour. All three drug regimens significantly increased the mean gastric pH value compared with the control group. Famotidine and ranitidine reduced the volume of gastric content in comparison with sodium citrate and the control group. However, the difference was significant only in the recovery room sample.
在114例接受上腹部手术的患者中，测试了法莫替丁（40毫克）、雷尼替丁（300毫克）和柠檬酸钠（30毫升）对胃pH值和胃容量的影响。插管后、手术结束时以及在恢复室停留一小时后，通过多孔管抽吸胃内容物。与对照组相比，所有三种药物方案均显著提高了平均胃pH值。与柠檬酸钠和对照组相比，法莫替丁和雷尼替丁减少了胃内容物的容量。然而，差异仅在恢复室样本中显著。
