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中国的脊柱关节炎。

Spondyloarthritis in China.

机构信息

Division of Rheumatology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.

出版信息

Curr Opin Rheumatol. 2013 Jul;25(4):460-7. doi: 10.1097/BOR.0b013e3283621b8c.

Abstract

PURPOSE OF REVIEW

Although scientists in China have generated a considerable amount of new information about spondyloarthritis (SpA) in recent years, part of it was published in Chinese. The aim of this review is to summarize all SpA articles for the benefit of English readers.

RECENT FINDINGS

In the field of epidemiology, prevalence of SpA in China has been updated, especially with regard to psoriatic arthritis (PsA). In the field of genetics, Chinese scientists have discovered new single-nucleotide polymorphism (SNP) sites association with ankylosing spondylitis (AS) in Han Chinese. In the field of treatment, tumour necrosis factor-alpha (TNF-α) antagonists are wildly used almost as a routine. The usefulness of certain Chinese traditional medicine is undergoing vigorous testing. In the field of diagnosis, ultrasound has been incorporated into the testing tools. In the field of monitoring of disease activity, Ankylosing Spondylitis Disease Activity Scores (ASDAS) has been validated in a cohort of Chinese SpA patients.

SUMMARY

Chinese scientists are using cutting-edge technology in the fields of research, diagnosis and management in SpA. What is needed are new approaches that can accommodate the large variations in socioeconomic status of various localities in the vast Chinese continent.

摘要

目的综述

尽管近年来中国科学家在脊柱关节炎(SpA)领域产生了相当多的新信息,但其中一部分是用中文发表的。本综述的目的是为了让英语读者了解所有的 SpA 文章。

最近的发现

在流行病学领域,中国 SpA 的患病率得到了更新,尤其是在银屑病关节炎(PsA)方面。在遗传学领域,中国科学家发现了与汉族强直性脊柱炎(AS)相关的新单核苷酸多态性(SNP)位点。在治疗领域,肿瘤坏死因子-α(TNF-α)拮抗剂被广泛应用,几乎成为常规治疗。某些中药的有效性正在进行积极的测试。在诊断领域,超声已被纳入检测工具。在疾病活动监测领域,强直性脊柱炎疾病活动评分(ASDAS)已在一组中国 SpA 患者中得到验证。

总结

中国科学家正在 SpA 的研究、诊断和管理领域使用最先进的技术。需要的是能够适应中国广大地区社会经济地位巨大差异的新方法。

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