Zhang Isabella, Zaorsky Nicholas G, Abraham John A, Tuluc Madalina, Curry Joseph M, Bar-Ad Voichita
Department of Radiation Oncology Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
Head Neck. 2014 Jul;36(7):E65-72. doi: 10.1002/hed.23373. Epub 2014 Feb 3.
We describe a 53-year-old man who presented with a painless neck mass and underwent a resection that identified the tumor as a low-grade chondrosarcoma of the hyoid bone. We reviewed the literature for diagnosis and management options of this exceptionally rare diagnosis.
We conducted a search of the published medical literature before September 2012 in MEDLINE and PubMed using the terms "chondrosarcoma" and "hyoid." The search led to 19 case reports. We then searched for recent advances in diagnosis and treatment.
Chondrosarcomas of the hyoid bone present as slow-growing, painless masses of the neck. CT and MRI are useful for imaging, but definitive diagnosis is made by biopsy.
The preferred treatment is complete surgical removal, whereas radiation is used as adjuvant therapy. Positive surgical margin is a significant risk factor for recurrence. Long-term follow-up is recommended because of recurrences many years later.
我们描述了一名53岁男性，其因无痛性颈部肿块就诊，接受切除术后病理诊断为舌骨低度软骨肉瘤。我们查阅了相关文献，以了解这种极为罕见疾病的诊断和治疗方法。
我们在2012年9月之前使用“软骨肉瘤”和“舌骨”这两个关键词在MEDLINE和PubMed数据库中检索已发表的医学文献。检索结果为19篇病例报告。随后我们又搜索了诊断和治疗方面的最新进展。
舌骨软骨肉瘤表现为颈部生长缓慢的无痛性肿块。CT和MRI对成像有帮助，但最终诊断需依靠活检。
首选治疗方法是完整手术切除，放疗用作辅助治疗。手术切缘阳性是复发的重要危险因素。鉴于多年后可能复发，建议进行长期随访。
