Amaral D, Zagalo C, Cardina C, Vera-Cruz P
Rev Laryngol Otol Rhinol (Bord). 2015;136(2):77-80.
Chondrosarcomas are cartilaginous tumors that range from low-grade tumors with low metastatic potential to high-grade aggressive tumors with premature and high metastatic rate. Low-grade types have few karyotype abnormalities and are near-diploid, while high-grade chondrosarcomas originate from complex karyotypes and are aneuploid. The most common karyotype aberrations found include 12q13-15 and 9p21 rearrangements. Here, it is presented a case of chondrosarcoma of the hyoid bone with its image, surgical procedure and pathological correlation as well as a review of the literature.
A sixty-three year old man presented with a large cervical mass located at submental level. The CT scan revealed a voluminous and well-limited mass of 5 x 4 x 3 cm located in the suprahyoid region. The operative finding revealed a grade 2 chondrosarcoma originating from the hyoid bone.
Chondrosarcoma of the. hyoid bone is a rare pathology, thus making it difficult to diagnose. Fine needle biopsies have high diagnostic accuracy, although correct grading is only obtained 46% of the time. CT scan is the golden standard to characterize tumor extension and origin. Surgical excision is the treatment of choice for chondrosarcoma.
软骨肉瘤是一种软骨肿瘤，范围从转移潜能低的低级别肿瘤到转移率高且发生早的高级别侵袭性肿瘤。低级别类型的核型异常较少，接近二倍体，而高级别软骨肉瘤起源于复杂核型，为非整倍体。最常见的核型畸变包括12q13 - 15和9p21重排。本文介绍了一例舌骨软骨肉瘤病例，包括其影像学表现、手术过程及病理相关性，并对相关文献进行了综述。
一名63岁男性患者，颏下水平出现一个巨大的颈部肿块。CT扫描显示舌骨上区域有一个大小为5×4×3 cm、边界清晰的巨大肿块。手术发现为起源于舌骨的2级软骨肉瘤。
舌骨软骨肉瘤是一种罕见的病理类型，因此诊断困难。细针穿刺活检具有较高的诊断准确性，不过正确分级的准确率仅为46%。CT扫描是确定肿瘤范围和起源的金标准。手术切除是软骨肉瘤的首选治疗方法。
