Ayan Murat, Taş Ufuk, Söğüt Erkan, Arıcı Semih, Karaman Serkan, Esen Mehmet, Demirtürk Fazlı
Department of Emergency Medicine, Gaziosmanpaşa University Faculty of Medicine, Tokat, Turkey.
Agri. 2013;25(2):78-82. doi: 10.5505/agri.2013.42103.
The aim of this study was to compare the efficiency of diclofenac sodium to paracetamol using a visual analog scale in the patients presenting to the emergency room with primary dysmenorrhea.
Group I (n=40) patients were diagnosed with primary dysmenorrhea and treated with paracetamol (1 gr intravenous) and Group II (n=40) patients were diagnosed with primary dysmenorrhea and treated with diclofenac sodium (75 mg intramuscular). In both groups, patients were 19-30 years old. In all groups, the intensity of the pain was ranked from 0 (no pain) to 10 (intolerable) using VAS. The VAS scores were compared between treatment groups.
Between two groups, there was no statistically significant difference in age, mean arterial pressure and pulse values. The initial VAS values of the first group were higher than that of 2nd group. Following treatment, in the 10th and 30th minutes, the VAS values were lower in Group I than Group II (p=0.00). The VAS values of each group were significantly different from each other on the 10th and 30th minutes. VAS values at the 10th and 30th minutes were lower compared to the initial values and the values in the 30th minute were lower relative to the 10th minute (p=0.00) in both treatment groups.
We can suggest that paracetamol is more efficient than diclofenac sodium in the treatment of primary dysmenorrhea.
本研究旨在使用视觉模拟评分法比较双氯芬酸钠与对乙酰氨基酚对急诊室原发性痛经患者的治疗效果。
第一组(n = 40)原发性痛经患者接受对乙酰氨基酚(1克静脉注射)治疗,第二组(n = 40)原发性痛经患者接受双氯芬酸钠(75毫克肌肉注射)治疗。两组患者年龄均为19 - 30岁。所有组中,使用视觉模拟评分法将疼痛强度从0(无疼痛)到10(无法忍受)进行排序。比较治疗组之间的视觉模拟评分法得分。
两组之间在年龄、平均动脉压和脉搏值方面无统计学显著差异。第一组的初始视觉模拟评分法值高于第二组。治疗后,在第10分钟和第30分钟时,第一组的视觉模拟评分法值低于第二组(p = 0.00)。每组在第10分钟和第30分钟时的视觉模拟评分法值彼此有显著差异。在两个治疗组中,第10分钟和第30分钟时的视觉模拟评分法值均低于初始值,且第30分钟时的值相对于第10分钟时更低(p = 0.00)。
我们可以认为在原发性痛经治疗中,对乙酰氨基酚比双氯芬酸钠更有效。