Shaffer Jonathan A, Kronish Ian M, Burg Matthew, Clemow Lynn, Edmondson Donald
Center for Behavioral Cardiovascular Health, Columbia University Medical Center, 622 West 168th Street, PH9-318, New York, NY, 10032, USA,
Ann Behav Med. 2013 Dec;46(3):349-57. doi: 10.1007/s12160-013-9512-8.
Symptoms of posttraumatic stress disorder (PTSD) after acute coronary syndrome (ACS) are associated with recurrent ACS events and mortality. Poor sleep may be a mechanism, but the association between PTSD and sleep after ACS is unknown.
This study aims to estimate the association between ACS-induced PTSD symptoms and self-reported sleep.
ACS-induced PTSD symptoms were assessed 1-month post-ACS in 188 adults using the Impact of Events Scale-Revised. Sleep was assessed using the Pittsburgh Sleep Quality Index. Linear and logistic regression models were used to determine whether PTSD symptoms were associated with self-reported sleep, independent of sociodemographic and clinical covariates.
In adjusted models, ACS-induced PTSD symptoms were associated with worse overall sleep (β = 0.22, p = 0.003) and greater impairment in six of seven components of sleep (all p values <0.05).
ACS-induced PTSD symptoms may be associated with poor sleep, which may explain why PTSD confers increased cardiovascular risk after ACS.
急性冠状动脉综合征(ACS)后创伤后应激障碍(PTSD)的症状与ACS复发事件及死亡率相关。睡眠不佳可能是一种机制,但PTSD与ACS后睡眠之间的关联尚不清楚。
本研究旨在评估ACS诱发的PTSD症状与自我报告睡眠之间的关联。
使用事件影响量表修订版对188名成年人在ACS后1个月时的ACS诱发PTSD症状进行评估。使用匹兹堡睡眠质量指数评估睡眠情况。采用线性和逻辑回归模型来确定PTSD症状是否与自我报告睡眠相关,且独立于社会人口统计学和临床协变量。
在调整模型中,ACS诱发的PTSD症状与整体睡眠较差相关(β = 0.22,p = 0.003),且与七个睡眠成分中的六个成分的更大损害相关(所有p值<0.05)。
ACS诱发的PTSD症状可能与睡眠不佳相关,这可能解释了为什么PTSD会增加ACS后的心血管风险。