Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
J Biomed Mater Res A. 2013 Sep;101(9):2449-55. doi: 10.1002/jbm.a.34811. Epub 2013 Jun 28.
This paper describes the discovery of the first inhibitors of angiogenesis; the discoveries that led to the development of the first biocompatible controlled release systems for macromolecules, and findings that helped to create the field of tissue engineering. In addition, new paradigms for creating biomaterials, early work on nanotechnology in medicine and intelligent drug delivery systems are discussed.
本文描述了第一代血管生成抑制剂的发现，第一代生物相容的大分子控释系统的发展所依据的发现，以及帮助创建组织工程领域的发现。此外，还讨论了创建生物材料的新范例、医学纳米技术的早期工作和智能药物输送系统。
