Amani Mohammed El Amine, Benabadji Nadjia, Benzian Zakaria, Amani Souad
Department of Endocrine and Diabetes, CHU Benzerdjeb, Oran, Algeria.
Indian J Nucl Med. 2012 Apr;27(2):124-6. doi: 10.4103/0972-3919.110718.
Thyroid ectopy is characterized by the presence of thyroid tissue outside its normal position resulting from a defect of the thyroid diverticulum migration from the base of the tongue until its final pre-tracheal position. One case is presented in a 12-year-old girl patient who consults for a failure to thrive estimated at less than three standard deviations (SD). Bone age was estimated at 8 years late compared to chronological age. The hormonal assessment showed hypothyroidism with negative thyroid antibodies. Cervical ultrasound was revealed thyroid parenchyma pre-dominantly left in place while sweeping the area under chin showed a nodular formation of the base of the tongue. Thyroid scan with technetium 99 m showed a selective uptake of radiotracer in sublingual position. Cervical computed tomography revealed a posterior median sublingual mass spontaneously hyperdense and enhancing sharply after injection of contrast. Treatment with thyroxine allowed obtaining euthyroidism. This case asks us to be careful before aetiological diagnosis of hypothyroidism in children, because although this is rare, the presence of a thyroid parenchyma up to the cervical ultrasound does not eliminate the presence of ectopic tissue.
甲状腺异位的特征是甲状腺组织出现在其正常位置之外，这是由于甲状腺憩室从舌根底部迁移至气管前最终位置的过程中出现缺陷所致。本文报告一例12岁女童患者，其因生长发育迟缓前来就诊，生长发育迟缓估计低于三个标准差（SD）。骨龄估计比实际年龄晚8岁。激素评估显示甲状腺功能减退且甲状腺抗体阴性。颈部超声检查显示甲状腺实质主要位于左侧，而扫描下巴下方区域时发现舌根部有结节形成。用锝99m进行的甲状腺扫描显示放射性示踪剂在舌下位置有选择性摄取。颈部计算机断层扫描显示舌后正中皮下有一肿块，自发高密度，注射造影剂后强化明显。使用甲状腺素治疗使甲状腺功能恢复正常。该病例提醒我们，在对儿童甲状腺功能减退进行病因诊断之前要谨慎，因为尽管这种情况罕见，但颈部超声检查显示存在甲状腺实质并不能排除异位组织的存在。
