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广泛侵袭性乳腺外佩吉特病：手术治疗

Extensive Invasive Extramammary Paget's Disease: Surgical Treatment.

作者信息

Wollina Uwe

机构信息

Department of Dermatology and Allergology, Academic Teaching Hospital, Friedrichstadt, Dresden, Germany.

出版信息

J Cutan Aesthet Surg. 2013 Jan;6(1):41-4. doi: 10.4103/0974-2077.110098.

DOI:10.4103/0974-2077.110098
PMID:23723606
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3663178/
Abstract

Extramammary Paget's disease is uncommon. Diagnosis has to be confirmed by histopathology. Treatment is a challenge in cases with extended tumors. We present a 70-year-old male patient with extensive genitoanal Paget's disease. Mohs surgery is the gold standard in such cases. Details of the surgical planning are discussed including wound bed preparation. Radiotherapy may be an alternative.

摘要

乳腺外佩吉特病并不常见。诊断必须通过组织病理学来证实。对于肿瘤范围较大的病例，治疗是一项挑战。我们报告一例70岁患有广泛的生殖器肛门佩吉特病的男性患者。在这种情况下，莫氏手术是金标准。讨论了手术规划的细节，包括创面准备。放疗可能是一种替代方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d5/3663178/f863b056bb0d/JCAS-6-41-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d5/3663178/3715337620f2/JCAS-6-41-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d5/3663178/13e653488b02/JCAS-6-41-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d5/3663178/ad0639f4ce87/JCAS-6-41-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d5/3663178/221a9499cf1b/JCAS-6-41-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d5/3663178/c08a26098442/JCAS-6-41-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d5/3663178/f863b056bb0d/JCAS-6-41-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d5/3663178/3715337620f2/JCAS-6-41-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d5/3663178/13e653488b02/JCAS-6-41-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d5/3663178/ad0639f4ce87/JCAS-6-41-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d5/3663178/221a9499cf1b/JCAS-6-41-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d5/3663178/c08a26098442/JCAS-6-41-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d5/3663178/f863b056bb0d/JCAS-6-41-g006.jpg

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Incomplete efficacy of 5-aminolevulinic acid (5 ALA) photodynamic therapy in the treatment of widespread extramammary Paget's disease.5-氨基酮戊酸（5-ALA）光动力疗法治疗广泛的乳腺外派杰氏病疗效不全。
Photodermatol Photoimmunol Photomed. 2012 Feb;28(1):53-5. doi: 10.1111/j.1600-0781.2011.00635.x.
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Treatment of vulvar Paget disease with topical imiquimod: a case report and review of the literature.
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Two cases of Paget's disease of scrotum in biological brothers.两例生物学兄弟患阴囊佩吉特病。
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外用咪喹莫特治疗外阴佩吉特病：1例报告并文献复习
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Automated 15-minute cytokeratin 7 immunostaining protocol for extramammary Paget's disease in Mohs micrographic surgery.用于莫氏显微外科手术中乳腺外佩吉特病的15分钟细胞角蛋白7免疫染色自动化方案。
Dermatol Surg. 2011 Dec;37(12):1811-5. doi: 10.1111/j.1524-4725.2011.02181.x. Epub 2011 Nov 7.
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