4-(2-甲氧基苯基)-2,6-二甲基-1,4-二氢吡啶-3,5-二羧酸二乙酯

Wang Ke, Wang Yifeng, Yao Minjie, Xu Danqian

Catalytic Hydrogenation Research Center, Zhejiang University of Technology, Hangzhou 310014, People's Republic of China.

Acta Crystallogr Sect E Struct Rep Online. 2013 Apr 24;69(Pt 5):o785. doi: 10.1107/S1600536813009951. Print 2013 May 1.

In the title compound, C20H25NO5, the di-hydro-pyridine ring adopts a flattened boat conformation. The meth-oxy-phenyl ring is almost perpendicular to the mean plane of the pyridine ring [dihedral angle = 88.42 (3)°]. The two carbonyl units adopt a synperiplanar conformation with respect to the double bonds in the di-hydro-pyridine ring. In the crystal, mol-ecules are connected by N-H⋯O hydrogen bonds into R 4 (4)(24) tetra-meric rings. A region of disordered electron density, located at the center of four adjacent mol-ecules, was treated with the SQUEEZE routine in PLATON [Spek (2009 ▶). Acta Cryst. D65, 148-155]. It is probably the result of traces of the solvent of crystallization and was not taken into account during the structure refinement.

在标题化合物C20H25NO5中，二氢吡啶环呈扁平船式构象。甲氧基苯基环几乎垂直于吡啶环的平均平面[二面角 = 88.42 (3)°]。两个羰基单元相对于二氢吡啶环中的双键呈顺叠构象。在晶体中，分子通过N—H⋯O氢键连接成R 4 (4)(24)四聚环。位于四个相邻分子中心的一个无序电子密度区域，用PLATON中的SQUEEZE程序[Spek (2009 ▶). Acta Cryst. D65, 148 - 155]进行了处理。它可能是结晶溶剂痕迹的结果，在结构精修过程中未予考虑。