Albawardi Alia Saeed, Castella Antonio, Almarzooqi Saeeda Saleh
College of Medicine & Health Sciences, Consultant Pathologist-Tawam Hospital Al Ain, United Arab Emirates.
Int J Clin Exp Med. 2013 May 22;6(5):346-50. Print 2013.
Lymphoplasmacytic lymphoma is an indolent malignancy of B cells and plasma cells. The disease presents in the adults with bone marrow and lymph nodes involvement. Extranodal involvement is rare but has been reported in spleen and liver. Herein, we present a case of a 50-year-old woman who underwent hysterectomy and salpingo-oophorectomy for irregular uterine bleeding. Histologic examination of uterine cervix, uterine walls and fallopian tubes reveal dense lymphoplasmacytic infiltrate that was most pronounced in ovaries. This is the first case report on lymphoplasmacytic lymphoma-Waldenström macroglobulinemia initially presenting and secondarily involving both ovaries and other gynecological organs.
淋巴浆细胞淋巴瘤是一种惰性B细胞和浆细胞恶性肿瘤。该疾病多见于成人，常累及骨髓和淋巴结。结外受累罕见，但脾脏和肝脏受累已有报道。在此，我们报告一例50岁女性，因不规则子宫出血接受子宫切除术和输卵管卵巢切除术。子宫颈、子宫壁和输卵管的组织学检查显示密集的淋巴浆细胞浸润，在卵巢中最为明显。这是首例关于淋巴浆细胞淋巴瘤-华氏巨球蛋白血症最初累及双侧卵巢及其他妇科器官的病例报告。
