平滑肌瘤、妇科癌前病变及恶性肿瘤患者中子宫内膜异位症和子宫腺肌病的发生率。
Frequency of endometriosis and adenomyosis in patients with leiomyomas, gynecologic premalignant, and malignant neoplasias.
作者信息
Nomelini R S, Ferreira F A, Borges R C, Adad S J, Murta E F C
机构信息
Oncological Research Institute (IPON), Discipline of Gynecology and Obstetrics, Federal University of the Triângulo Mineiro, Uberaba, MG, Brazil.
出版信息
Clin Exp Obstet Gynecol. 2013;40(1):40-4.
OBJECTIVE
This study investigated the association between gynecological neoplasms, endometriosis, and adenomyosis in women who underwent surgical treatment for gynecological cancer and uterine leiomyoma during reproductive years or after menopause.
MATERIALS AND METHODS
Information was collected from patient records from the Hospital's database from 1985 to 2007. The study included 502 women, of which 375 were premenopausal and 132 were postmenopausal.
RESULTS
A significant association was observed between the occurrence of adenomyosis in cancer in women with four or more pregnancies, and in women aged over 40 years (p < 0.0001). The frequency of adenomyosis was significantly higher than the frequency of endometriosis for cancer in two sites (p = 0.0419) or for leiomyomas (p < 0.0001).
CONCLUSION
Therefore adenomyosis is more frequently found than endometriosis in women with leiomyomas or cancer in two sites in premenopausal women, and clinicians need to be aware of patients with adenomyosis and the risk of cancer.
目的
本研究调查了在生育年龄或绝经后接受妇科癌症和子宫平滑肌瘤手术治疗的女性中，妇科肿瘤、子宫内膜异位症和子宫腺肌病之间的关联。
材料与方法
从1985年至2007年医院数据库的患者记录中收集信息。该研究纳入了502名女性，其中375名处于绝经前，132名处于绝经后。
结果
在有四次或更多次妊娠的女性以及40岁以上的女性中，癌症患者子宫腺肌病的发生率之间存在显著关联（p < 0.0001）。在两个部位的癌症患者中（p = 0.0419）或平滑肌瘤患者中（p < 0.0001），子宫腺肌病的发生率显著高于子宫内膜异位症的发生率。
结论
因此，在绝经前患有平滑肌瘤或两个部位癌症的女性中，子宫腺肌病比子宫内膜异位症更常见，临床医生需要了解子宫腺肌病患者及其患癌风险。
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