Tidebrant G, Asztely M, Lukes P, Tylén U
Department of Radiology, Sahlgrenska Sjukhuset, Gothenburg, Sweden.
Acta Radiol. 1990 Mar;31(2):161-6.
Non-enhanced, bolus contrast medium enhanced and 4 to 6 hours delayed computed tomography of the liver was performed in a prospective study of 53 patients. Forty patients had focal lesions, in 12 of these they were hypervascular. Contrast medium was administered as an initial bolus followed by a rapid injection of meglumine metrizoate (Isopaque Cerebral). The total iodine dose varied between 56 and 63 g, which gave an average increase in attenuation of 14 HU in normal parenchyma comparing delayed with non-enhanced scanning. Presence and extent of focal lesions were evaluated in a randomized and independent analysis by two radiologists. The percentage of examinations with correct tumour description was higher with bolus scanning (observer I 73%, observer II 75%) and delayed scanning (observer I 75%, observer II 78%) than with non-enhanced scanning (observers I and II 67%). An optimal bolus technique requires an exact timing of the contrast medium administration and scanning. Delayed scanning provides an excellent supplement when the bolus examination is suboptimal or shows equivocal findings.
在一项对53例患者的前瞻性研究中，对肝脏进行了非增强、团注造影剂增强及4至6小时延迟计算机断层扫描。40例患者有局灶性病变，其中12例为高血供病变。造影剂以初始团注给药，随后快速注射葡甲胺双碘苯酸盐（异泛影葡胺）。总碘剂量在56至63克之间，延迟扫描与非增强扫描相比，正常实质的衰减平均增加14HU。两名放射科医生通过随机独立分析评估局灶性病变的存在情况和范围。团注扫描（观察者I为73%，观察者II为75%）和延迟扫描（观察者I为75%，观察者II为78%）时对肿瘤描述正确的检查百分比高于非增强扫描（观察者I和II均为67%）。最佳团注技术需要精确的造影剂给药时间和扫描时间。当团注检查不理想或结果不明确时，延迟扫描可提供极好的补充。
