Division of Cosmetic Science, University of Hamburg, Hamburg, Germany.
Skin Res Technol. 2014 Feb;20(1):30-6. doi: 10.1111/srt.12079. Epub 2013 May 31.
The assessment of wrinkle severity is an important evaluation criterion to determine the efficacy of aesthetic treatments. Aim of the present study was to compare Validated Assessment Scales (VAS) and 3D fringe projection (PRIMOS(®) ) for the evaluation of facial wrinkles in men and to determine standard values for each level of the VAS.
150 male subjects (20 to 70 years) were selected following strict criteria. Wrinkle severity at periorbital, glabella and forehead lines was evaluated using the 3D fringe projection and 5-point photonumeric VAS. The results of both methods were matched by determining quantitative values for each level of the clinical rating scale.
High average correlation with age was found for VAS, Wd, maxWd, lWd, Wv, aWa and pWa. With a Wd of 60 to 70μm crow's feet and forehead lines are pronounced first, whereas glabella lines develop in subject's mid-forties, by an Wd of 180μm. Wrinkle severity increases at all locations every 10 years of age by one level of the VAS. This increase corresponds to an increase of Wd about 100 μm at glabella and forehead lines, and about 50 μm at crow's feet.
The presented reference values for the Validated Assessment Scale are an important step towards an optimized assessment of skin aging and aesthetic dermatological treatments. The data helps to combine the precession of a biophysical measurement with the practical relevance of a clinical rating.
皱纹严重程度的评估是判断美容治疗效果的重要评价标准。本研究旨在比较验证性评估量表（VAS）和三维边缘投影（PRIMOS®）在男性面部皱纹评估中的作用，并确定 VAS 每个等级的标准值。
根据严格的标准选择了 150 名男性受试者（20-70 岁）。使用三维边缘投影和 5 分光电数字 VAS 评估眶周、眉间和额部皱纹的严重程度。通过确定临床评分量表每个等级的定量值，使两种方法的结果相匹配。
VAS、Wd、maxWd、lWd、Wv、aWa 和 pWa 与年龄的平均相关性较高。当 Wd 为 60-70μm 时，鱼尾纹和额部皱纹首先出现，而眉间纹则在 40 多岁时出现，Wd 为 180μm。在所有部位，年龄每增加 10 岁，VAS 的等级就会增加一级。这种增加相当于眉间纹和额部皱纹的 Wd 增加约 100μm，鱼尾纹增加约 50μm。
本研究提出的验证性评估量表参考值是优化皮肤老化和美容皮肤科治疗评估的重要一步。该数据有助于将生物物理测量的精度与临床评分的实际相关性结合起来。
