Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
J Dermatol. 2013 Aug;40(8):632-4. doi: 10.1111/1346-8138.12203. Epub 2013 Jun 3.
Behçet's disease is a systemic inflammatory disorder with chronic remissions and relapses. Involvement of the central nervous system, called neuro-Behçet's disease (NBD), is a serious complication. Although corticosteroids and immunosuppressive agents are used, there is no definite standard of treatment with long term-effects for NBD. Here, we report a female case with NBD successfully treated by infliximab and corticosteroids for 2 years. Our report suggests treatment with infliximab may be effective for long-term remission of NBD.
贝赫切特病是一种全身炎症性疾病，具有慢性缓解和复发的特点。中枢神经系统受累，称为神经贝赫切特病（NBD），是一种严重的并发症。尽管使用了皮质类固醇和免疫抑制剂，但 NBD 的治疗尚无长期效果的明确标准。在这里，我们报告了一例 NBD 女性病例，经英夫利昔单抗和皮质类固醇治疗 2 年成功治愈。我们的报告表明，英夫利昔单抗治疗可能对 NBD 的长期缓解有效。
