Sarwar Haroon, McGrath Hugh, Espinoza Luis R
Section of Rheumatology, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA.
J Rheumatol. 2005 Jan;32(1):181-3.
Behçet's disease is a chronic relapsing form of vasculitis affecting multiple organs. Central nervous system involvement is a common presentation. Tumor necrosis factor-alpha (TNF-alpha) is considered to play a major role in the disease pathogenesis. We describe a patient with a long history of neuro-Behçet's disease who showed a remarkable response to infliximab therapy. Given the variable and limited success of other interventions, the use of anti-TNF-alpha therapy seems to be effective for patients with refractory disease.
白塞病是一种影响多个器官的慢性复发性血管炎。中枢神经系统受累是常见表现。肿瘤坏死因子-α（TNF-α）被认为在该病发病机制中起主要作用。我们描述了一名有神经白塞病长期病史的患者，其对英夫利昔单抗治疗表现出显著反应。鉴于其他干预措施效果不一且有限，抗TNF-α治疗似乎对难治性疾病患者有效。
