Gurbuzler Levent, Inanir Ahmet, Yelken Kursat, Koc Sema, Eyibilen Ahmet, Uysal Ismail Onder
Gaziomanpasa University Medicine Faculty, Department of Otolaryngology, Muhittin Füsunoğlu Street, 60100 Tokat, Turkey.
Auris Nasus Larynx. 2013 Dec;40(6):554-7. doi: 10.1016/j.anl.2013.04.002. Epub 2013 May 30.
To investigate several perceptual, acoustic and aerodynamic voice evaluation parameters in Fibromyalgia patients.
A total number of 30 Fibromyalgia patients had voice evaluations by means of laryngostroboscopy, acoustic analysis (jitter, shimmer, and harmonic to noise ratio), aerodynamic measurements (maximum phonation time, s/z ratio), and perceptual analysis (GRBAS and Voice Handicap Index-10 scales). Data obtained from the patients was compared to control subjects.
Mean intensity was found to be significantly higher in control subjects (73.70±4.73dB) than Fibromyalgia patients (64.50±6.92dB), (p<0.001). There was no statistically significant difference in fundamental frequency, perturbation parameters (jitter and shimmer) and harmonic to noise ratio between groups. Maximum phonation time in control subjects (22.53±4.95s) was found to be significantly longer than Fibromyalgia patients (16.07±4.87s), (p<0.001), and s/z ratio was found to be nearly equal between patients (1.00±0.24) and control subjects (0.96±0.16). On the basis of perceptual evaluation by using a GRBAS scale, the patients showed a mean score of 2.50±1.97 and the control group showed a mean score of 0.56±1.04 (p<0.001). "Grade" and "asthenia" parameters of GRBAS scale in Fibromyalgia patients were significantly different from the parameters of control group (p<0.001). The Voice Handicap Index-10 scales revealed a mean score of 7.90±7.58 in Fibromyalgia patients and 1.83±2.82 in control subjects (p<0.001).
Fibromyalgia impairs perceived voice quality either in patient self evaluated or in clinician evaluated rating scales. Furthermore, the results confirm that Fibromyalgia caused short maximum phonation time and low voice intensity. This study is the first report with regards to voice evaluation in Fibromyalgia and in order to make a generalization further researches are needed.
研究纤维肌痛患者的几种嗓音感知、声学和空气动力学评估参数。
共有30名纤维肌痛患者通过喉动态镜检查、声学分析（抖动、闪烁和信噪比）、空气动力学测量（最长发声时间、s/z比）和感知分析（GRBAS和嗓音障碍指数-10量表）进行嗓音评估。将患者获得的数据与对照组进行比较。
发现对照组的平均声强（73.70±4.73dB）显著高于纤维肌痛患者（64.50±6.92dB），（p<0.001）。两组之间的基频、微扰参数（抖动和闪烁）和信噪比无统计学显著差异。发现对照组的最长发声时间（22.53±4.95秒）显著长于纤维肌痛患者（16.07±4.87秒），（p<0.001），并且患者（1.00±0.24）和对照组（0.96±0.16）之间的s/z比几乎相等。根据使用GRBAS量表的感知评估，患者的平均得分为2.50±1.97，对照组的平均得分为0.56±1.04（p<0.001）。纤维肌痛患者GRBAS量表的“等级”和“无力”参数与对照组的参数有显著差异（p<0.001）。嗓音障碍指数-10量表显示纤维肌痛患者的平均得分为7.90±7.58，对照组为1.83±2.82（p<0.001）。
纤维肌痛会损害患者自我评估或临床医生评估量表中的嗓音感知质量。此外，结果证实纤维肌痛导致最长发声时间缩短和声强降低。本研究是关于纤维肌痛嗓音评估的首篇报告，为了进行推广，还需要进一步研究。
