Department of Rehabilitation Medicine, National Health Insurance Corporation Ilsan Hospital, Gyeonggi-do, Republic of Korea.
Arch Phys Med Rehabil. 2013 Nov;94(11):2151-6. doi: 10.1016/j.apmr.2013.05.008. Epub 2013 May 28.
To provide a quantitative analysis of ultrasonographic measurements and possible pathophysiology of carpal tunnel syndrome by comparing cross-sectional areas of the median nerve, carpal tunnel, and nerve/tunnel index and the difference in ultrasonographic findings between affected and nonaffected hands and between sexes.
Blinded comparison study.
Secondary referral and training hospital of institutional practice.
Patients (N=51; 42 women, 9 men) with suspected carpal tunnel syndrome who underwent sonography within 1 week after the electrodiagnostic study.
Not applicable.
Electrodiagnostic and ultrasonographic studies were conducted on both upper extremities. Cross-sectional areas of the median nerve and carpal tunnel were measured at 2 separate levels; proximal and distal cross-sectional areas of the carpal tunnel were each measured at the scaphoid-pisiform and trapezium-hamate levels, respectively.
Comparison between normative (n=24) and abnormal hands (n=78) revealed the following: the mean proximal cross-sectional areas of the median nerve, carpal tunnel, and nerve/tunnel index of electrodiagnostically normative hands were 10.941mm(2), 192.43mm(2), and 5.635%, respectively, whereas those of abnormal hands were 13.74mm(2), 208.87mm(2), and 6.693%, respectively, showing statistically significant differences for all (P<.05). Distal measurements of the cross-sectional area of the median nerve, carpal tunnel, and nerve/tunnel index were 10.088mm(2), 150.4mm(2), and 6.762%, respectively, in normative hands, and 11.178mm(2), 149.6mm(2), and 7.493%, respectively, in abnormal hands, showing no statistically significant differences (P>.05). In women, proximal cross-sectional areas of the median nerve and nerve/tunnel index of abnormal hands showed statistically significant differences, but no ultrasonographic measurement with a statistically significant difference was observed in men.
Compared with nonaffected hands, the proximal cross-sectional areas of the median nerve and carpal tunnel were greater, but the distal ultrasonographic measurements were not in affected hands. Ultrasonographic findings of carpal tunnel syndrome were different according to sex.
通过比较正中神经、腕管的横截面积、神经/管指数以及患病手与非患病手、男女之间的超声检查结果差异，对腕管综合征的超声测量和可能的病理生理学进行定量分析。
盲法比较研究。
机构实践的二级转诊和培训医院。
51 名（42 名女性，9 名男性）疑似腕管综合征患者，在电诊断研究后 1 周内行超声检查。
无。
对双侧上肢进行电诊断和超声检查。在 2 个不同水平测量正中神经和腕管的横截面积；分别在舟状骨-豆状骨和梯形-钩骨水平测量腕管的近端和远端横截面积。
与正常（n=24）手相比，异常（n=78）手的测量结果如下：电诊断正常手的正中神经近端横截面积、腕管横截面积和神经/管指数分别为 10.941mm²、192.43mm²和 5.635%，而异常手分别为 13.74mm²、208.87mm²和 6.693%，所有差异均具有统计学意义（P<.05）。正中神经远端横截面积、腕管横截面积和神经/管指数在正常手中分别为 10.088mm²、150.4mm²和 6.762%，在异常手中分别为 11.178mm²、149.6mm²和 7.493%，差异无统计学意义（P>.05）。在女性中，异常手的正中神经近端横截面积和神经/管指数存在统计学差异，但男性中未观察到具有统计学差异的超声测量结果。
与非患病手相比，患病手的正中神经近端横截面积和腕管较大，但远端超声测量结果无差异。腕管综合征的超声表现因性别而异。
