鱼油能预防血液透析患者猝死吗？

Fish oil for prevention of sudden death in hemodialysis patients?

机构信息

Department of Internal Medicine, Service of Nephrology, University Hospital (CHUV), Lausanne, Switzerland.

出版信息

Kidney Int. 2013 Jun;83(6):993-5. doi: 10.1038/ki.2013.54.

DOI:10.1038/ki.2013.54

Abstract

Friedman et al. report that hemodialysis patients with the highest levels of n-3 fatty acids had impressively low odds of sudden cardiac death. The study is limited by a small sample size, and the analysis relies on only a single baseline measurement of blood levels. Recent randomized evidence indeed fails to support that n-3 fatty acids may prevent sudden death in nonrenal patients. More evidence is needed to advocate fish oil in this setting.

摘要

弗里德曼等人报告称，血液透析患者体内 n-3 脂肪酸水平最高者发生心源性猝死的几率低得惊人。该研究的局限性在于样本量小，且分析仅依赖于单次基线血液水平测量。最近的随机对照证据确实不支持 n-3 脂肪酸可预防非肾脏患者的猝死。该治疗方案还需要更多证据支持。