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[宣威肺癌危险因素的病例对照研究]

[A case-control study of lung cancer risk factors in Xuanwei].

作者信息

Liu Z

机构信息

Institute of Environmental Health & Engineering, Chinese Academy of Preventive Medicine.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 1990 Apr;11(2):79-83.

PMID:2372823
Abstract

In Xuanwei County, Yunnan Province, lung cancer mortality is the highest in China. The former studies showed that indoor burning of "smokey" coal was an important cause for high incidence of Xuanwei lung cancer. The 1:Mi matched case-control study was undertaken to examine the association with other risk factors such as smoking. 110 cases of primary lung cancer newly diagnosed and 426 controls individually matched were interviewed. Conditional logistic regression was employed to examine the effect modification and to control confounding. The analytic results showed that smoking was one of the risk factors of Xuanwei male lung cancer. No relation was found between passive smoking and female lung cancer. The association was observed for familial history of lung cancer.

摘要

在云南省宣威县,肺癌死亡率居全国之首。以往的研究表明,室内燃烧“冒烟”煤是宣威肺癌高发的一个重要原因。开展了一项1:M匹配的病例对照研究,以检验与吸烟等其他危险因素的关联。对110例新诊断的原发性肺癌病例和426例个体匹配的对照进行了访谈。采用条件逻辑回归来检验效应修饰并控制混杂因素。分析结果表明,吸烟是宣威男性肺癌的危险因素之一。未发现被动吸烟与女性肺癌之间存在关联。观察到肺癌家族史与肺癌存在关联。

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