通过一种新的金属部件加工方法减少全膝关节假体聚乙烯磨损。
Total knee prosthesis polyethylene wear reduction by a new metal part finishing method.
机构信息
Department of Clinical and Molecular Sciences, School of Medicine, Università Politecnica delle Marche, Ancona - Italy.
出版信息
J Appl Biomater Funct Mater. 2013 Sep 13;11(2):e99-e105. doi: 10.5301/JABFM.5000153.
PURPOSE
The purpose of this study was to assess a new metal component finishing designed to improve total knee prosthesis durability. Wear of ultrahigh molecular-weight polyethylene (UHMWPE), with generation of submicrometer- and micrometer-sized particles, has been associated with osteolysis and artificial joint failure. Wear extent is influenced by several factors, some of which are related to manufacturing.
METHODS
UHMWPE wear was assessed in metal prosthesis components finished with the Microloy® technology and in traditionally finished components by wear simulation experiments (pin on disk and knee simulator tests) and analysis of wear debris.
RESULTS
Microloy®-finished prosthesis showed a 48.5% reduction in UHMWPE total weight loss compared with traditional components (P=0.002). A statistically significant (P<0.05) reduction of UHMWPE debris were detected from the Microloy®-finished compared with the traditionally finished components.
CONCLUSIONS
These findings suggest the Microloy® metal finishing may enhance the long-term performance of knee prostheses.
目的
本研究旨在评估一种新的金属部件表面处理技术，旨在提高全膝关节假体的耐用性。超高分子量聚乙烯（UHMWPE）的磨损会产生亚微米和微米级颗粒，与骨溶解和人工关节失效有关。磨损程度受多种因素影响，其中一些与制造有关。
方法
通过磨损模拟实验（销盘和膝关节模拟器试验）和磨损碎片分析，评估了采用 Microloy®技术和传统方法处理的金属假体部件中 UHMWPE 的磨损情况。
结果
与传统部件相比，Microloy®处理的假体的 UHMWPE 总重量损失减少了 48.5%（P=0.002）。从 Microloy®处理的部件中检测到的 UHMWPE 碎片明显少于传统处理的部件（P<0.05）。
结论
这些发现表明，Microloy®金属表面处理可能会提高膝关节假体的长期性能。
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