The University of Texas Medical School at Houston, Houston, Texas.
Head Neck. 2013 Nov;35(11):1551-7. doi: 10.1002/hed.23203. Epub 2013 Jun 1.
Mesenchymal malignancies of salivary origin are rare and are histologically diverse. We reviewed our experience with these tumors, as well as the published literature, with an emphasis on treatment modalities and prognosis.
We identified 17 patients treated for malignant mesenchymal cell tumors at The University of Texas MD Anderson Cancer Center between 1990 and 2007. We compared our results to the literature from January 1990 to July 2010.
Tumors were located primarily in the parotid gland and were primarily T1 tumors (<5 cm). All patients were treated with surgical resection, and 13 patients were given adjuvant therapy. Seven patients (41%) had recurrence, and 4 developed distant metastases. The overall 5-year and 10-year survival rates were 42% and 20%, respectively.
Our case series and literature review show that sarcomas of the salivary glands have a high rate of recurrence and are associated with a poor prognosis.
唾液来源的间叶性恶性肿瘤较为罕见，且组织学表现多样。我们回顾了我们在这些肿瘤方面的经验，以及已发表的文献，重点介绍了治疗方式和预后。
我们在 1990 年至 2007 年间于德克萨斯大学 MD 安德森癌症中心鉴定了 17 例接受恶性间叶细胞肿瘤治疗的患者。我们将我们的结果与 1990 年 1 月至 2010 年 7 月的文献进行了比较。
肿瘤主要位于腮腺，且主要为 T1 期肿瘤（<5cm）。所有患者均接受了手术切除，13 例患者接受了辅助治疗。7 例（41%）患者复发，4 例患者发生远处转移。总体 5 年和 10 年生存率分别为 42%和 20%。
我们的病例系列和文献复习表明，唾液腺肉瘤具有较高的复发率，且预后不良。
