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[云南1893例变应性鼻炎患者对吸入性变应原的致敏情况]

[Prevalence of sensitization to aeroallergens in 1 893 patients with allergic rhinitis in Yunnan].

作者信息

Li Sisi, Yu Yongmei, Ruan Biao, Liu Ben, Zhao Xiaoyang, Qiu Jiwei

机构信息

Kunming Medical University, Kunming, 650032, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Mar;27(5):246-50.

Abstract

OBJECTIVE

To investigate which aeroallergens were prevalent in patients with allergic rhinitis in Yunnan.

METHOD

Retrospective analysis of the medical records of intradermal test performed in 1893 AR patients. The samples were divided into four age groups: 4-17-year-olds, > 17-35-year-olds, > 35-50-year-olds and > 50-70-year-olds. According to gender,the samples were decided into two groups: the males and the females. The positive rate of aeroallergens were compared among the groups.

RESULT

(1)The total positive rate of intradermal test was 70.1%. The top ten allergens were as follow: dermatophagoides pteronyssinus, dermatophagoides farina, house dust, pollen of the summer and autumn, alnus nepalensis, chenopodiaceae, mugwort, poaceae, brassica and cockroach. (2) In all groups,patients with triple positive allergens were the most common,followed by dual positive allergens and single positive allergen. (3) Among the top ten allergens, the top three positive ones in all groups were dermatophagoides pteronyssinus, dermatophagoides farina and house dust. And there were significant differences between 4-17-year-olds group and the other age groups (P < 0.01). (4) There was no significant difference between male and female patients in distribution of aeroallergens except House dust and mite.

CONCLUSION

The most common allergen in patients with allergic rhinitis in Yunnan is mite,the follow are pollen of the summer and autumn, alnus nepalensis, chenopodiaceae, mugwort, poaceae, and brassica. The distribution of aeroallergens are different among the age groups, but has no evident correlation with gender.

摘要

目的

调查云南变应性鼻炎患者中流行的气传变应原。

方法

回顾性分析1893例变应性鼻炎患者皮内试验的病历资料。样本分为四个年龄组:4 - 17岁、>17 - 35岁、>35 - 50岁和>50 - 70岁。根据性别,样本分为两组:男性和女性。比较各组中气传变应原的阳性率。

结果

(1)皮内试验总阳性率为70.1%。前十位变应原如下:屋尘螨、粉尘螨、屋尘、夏秋花粉、尼泊尔桤木、藜科、艾蒿、禾本科、芸苔属和蟑螂。(2)在所有组中,三重阳性变应原的患者最常见,其次是双重阳性变应原和单一阳性变应原。(3)在前十位变应原中,所有组中阳性率最高的前三位是屋尘螨、粉尘螨和屋尘。4 - 17岁组与其他年龄组之间存在显著差异(P < 0.01)。(4)除屋尘和螨外,男性和女性患者气传变应原分布无显著差异。

结论

云南变应性鼻炎患者中最常见的变应原是螨,其次是夏秋花粉、尼泊尔桤木、藜科、艾蒿、禾本科和芸苔属。气传变应原的分布在各年龄组之间有所不同,但与性别无明显相关性。

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