Uccello-Barretta Gloria, Balzano Federica
Dipartimento di Chimica e Chimica Industriale, Università di Pisa, via Risorgimento 35, 56126, Pisa, Italy,
Top Curr Chem. 2013;341:69-131. doi: 10.1007/128_2013_445.
This chapter will describe the general features and main categories of chiral solvating agents (CSAs) for NMR spectroscopy, spanning from low-medium sized CSAs to macrocyclic ones. CSAs based on chiral ionic liquids (CILs) will be introduced in view of their increasing popularity, and, finally, a short paragraph will be dedicated to special applications of CSAs in particular experimental conditions. Several valuable works, which are mainly devoted to investigate enantiodifferentiation mechanisms by NMR, will not be discussed. The main objective is to identify the current trend in the research areas dedicated to the development of new CSAs for NMR spectroscopy.
本章将描述用于核磁共振光谱的手性溶剂化剂（CSA）的一般特征和主要类别，范围从中小型CSA到大环CSA。鉴于基于手性离子液体（CIL）的CSA越来越受欢迎，将对其进行介绍，最后，将用一小段篇幅专门介绍CSA在特定实验条件下的特殊应用。一些主要致力于通过核磁共振研究对映体鉴别机制的有价值的工作将不做讨论。主要目的是确定致力于开发用于核磁共振光谱的新型CSA的研究领域的当前趋势。
