Department of Plastic and Reconstructive Surgery, Clínica Universidad de Navarra, Navarra, Spain.
Head Neck. 2014 Jan;36(1):113-9. doi: 10.1002/hed.23276. Epub 2013 Jun 1.
There is much controversy regarding the effect of radiotherapy on facial nerve regeneration. However, the effect of brachytherapy has not been studied.
Fifty-three patients underwent total parotidectomy of which 13 were radical with immediate facial nerve repair with sural nerve grafts. Six patients (group 1) did not receive adjuvant treatment whereas 7 patients (group 2) received postoperative brachytherapy plus radiotherapy. Functional outcomes were compared using Facial Clima.
Mean percentage of blink recovery was 92.6 ± 4.2 for group 1 and 90.7 ± 5.2 for group 2 (p = .37). Mean percentage of commissural excursion restoration was 78.1 ± 3.5 for group 1 and 74.9 ± 5.9 for group 2 (p = .17). Mean time from surgery to first movement was 5.7 ± 0.9 months for group 1 and 6.3 ± 0.5 months for group 2 (p = .15).
Brachytherapy plus radiotherapy does not affect the functional outcomes of immediate facial nerve repair with nerve grafts.
关于放射治疗对面神经再生的影响存在很多争议。然而，近距离放射治疗的效果尚未得到研究。
53 例患者接受了腮腺全切除术，其中 13 例为根治性手术，立即进行面神经修复和腓肠神经移植。6 例患者（第 1 组）未接受辅助治疗，而 7 例患者（第 2 组）接受了术后近距离放射治疗加放射治疗。使用 Facial Clima 比较功能结果。
第 1 组眨眼恢复的平均百分比为 92.6±4.2，第 2 组为 90.7±5.2（p=0.37）。第 1 组口角运动恢复的平均百分比为 78.1±3.5，第 2 组为 74.9±5.9（p=0.17）。第 1 组从手术到第一次运动的平均时间为 5.7±0.9 个月，第 2 组为 6.3±0.5 个月（p=0.15）。
近距离放射治疗加放射治疗并不影响神经移植即刻面神经修复的功能结果。
