1 Analytical Epidemiology and Health Impact Unit, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Eur J Public Health. 2014 Feb;24(1):98-100. doi: 10.1093/eurpub/ckt056. Epub 2013 May 31.
We analysed presentation, treatment and survival in a representative population-based sample of 3753 Italian colorectal cancer cases, diagnosed 2003-05: 70% were >65 years, 44% stage I-II, 27% stage IV and 92% received surgery. Chemotherapy was given to 58% of stage III colon cases, radiotherapy to 25% of rectal cases. Four percent of surgical cases underwent endoscopic polypectomy, and in 57% ≥11 lymph nodes were examined. Five-year relative survival was good (60%), independent of sex and site. Adherence to treatment guidelines was satisfactory, but wider use of faecal blood testing and colonoscopy will anticipate stage at diagnosis and likely improve survival.
我们分析了在一个具有代表性的意大利基于人群的 3753 例结直肠癌病例样本中的表现、治疗和生存情况，这些病例诊断于 2003-05 年：70%的患者年龄大于 65 岁，44%处于 I-II 期，27%处于 IV 期，92%接受了手术。58%的 III 期结肠癌患者接受了化疗，25%的直肠癌患者接受了放疗。4%的手术病例接受了内镜息肉切除术，57%的病例检查了≥11 个淋巴结。5 年相对生存率较高（60%），与性别和部位无关。治疗指南的依从性令人满意，但更广泛地使用粪便潜血试验和结肠镜检查将预测诊断时的分期，并可能提高生存率。
