VanHaltren Karen, Malhotra Atul
J Pediatr Endocrinol Metab. 2013;26(9-10):861-5. doi: 10.1515/jpem-2013-0012.
Infants of diabetic mothers (IDMs) are at risk of hypoglycaemia in the neonatal period. The prediction of which of these infants are at higher risk of developing hypoglycaemia is complex.
To determine the characteristics of infants of diabetic mothers who are more likely to need an admission to the neonatal intensive care unit to manage their hypoglycaemia.
Retrospective chart review of maternal and infant characteristics of 'at-risk' infants. Electronic patient records and neonatal and obstetric database accessed to obtain data.
A total of 326 infants were identified in a study period accessible to electronic patient records. Macrosomia was present in 15% of the infants. Hypoglycaemic episodes occurred in 109 (33.4%) infants. Maternal diabetes type, HbA1c, prematurity, macrosomia, and temperature instability were identified as risk factors most commonly associated in infants who actually went on to develop hypoglycaemia.
A weighted risk score to predict hypoglycaemia in this at-risk population may serve to rationalise admission to the neonatal unit and management of IDMs.
糖尿病母亲所生婴儿（IDM）在新生儿期有发生低血糖的风险。预测哪些婴儿发生低血糖的风险较高是复杂的。
确定更有可能需要入住新生儿重症监护病房来处理低血糖的糖尿病母亲所生婴儿的特征。
对“高危”婴儿的母婴特征进行回顾性病历审查。通过访问电子病历以及新生儿和产科数据库来获取数据。
在可获取电子病历的研究期间共确定了326名婴儿。15%的婴儿为巨大儿。109名（33.4%）婴儿发生了低血糖发作。母亲糖尿病类型、糖化血红蛋白、早产、巨大儿和体温不稳定被确定为实际发生低血糖的婴儿中最常见的相关危险因素。
用于预测该高危人群低血糖的加权风险评分可能有助于使新生儿病房的收治和糖尿病母亲所生婴儿的管理更加合理。
