对患有和未患有继发于颅交叉韧带断裂的骨关节炎的犬只进行维生素A、维生素E、硒和L-乳酸的测量。
Measurement of vitamin A, vitamin E, selenium, and L-lactate in dogs with and without osteoarthritis secondary to ruptured cranial cruciate ligament.
作者信息
de Oliveira El-Warrak Alexander, Rouma Mouhamed, Amoroso Audrey, Boysen Soren R, Chorfi Younés
机构信息
Département des Sciences Cliniques, Faculté de médecine vétérinaire, 3200, Sicotte CP 5000, Saint-Hyacinthe, Quebec J2S 7C6.
出版信息
Can Vet J. 2012 Dec;53(12):1285-8.
This study compared vitamin A, vitamin E, selenium (Se), and L-lactate in blood and synovial fluid in 2 groups of 6 dogs; a control group (without OA) and an osteoarthritic group with spontaneous cranial cruciate ligament rupture and OA. Concentrations of vitamin E were significantly higher in serum than in synovial fluid in both OA (P = 0.006) and control (P = 0.0008) groups. Vitamin E concentration in synovial fluid was significantly higher in the OA group than in the control group (P = 0.009). Concentrations of Se were significantly higher in serum than in synovial fluid in both OA (P = 0.003) and control (P = 0.0006) groups. There were no significant differences in levels of Se, vitamin A, and L-lactate between the 2 groups. This is the first study to show an increased concentration of vitamin E in the synovial fluid of dogs with OA compared with dogs that did not have OA.
本研究比较了两组各6只犬血液和滑液中维生素A、维生素E、硒（Se）和L-乳酸的含量；一组为对照组（无骨关节炎），另一组为患有自发性颅交叉韧带断裂和骨关节炎的骨关节炎组。在骨关节炎组（P = 0.006）和对照组（P = 0.0008）中，血清中维生素E的浓度均显著高于滑液中的浓度。骨关节炎组滑液中维生素E的浓度显著高于对照组（P = 0.009）。在骨关节炎组（P = 0.003）和对照组（P = 0.0006）中，血清中硒的浓度均显著高于滑液中的浓度。两组之间硒、维生素A和L-乳酸水平无显著差异。这是第一项表明与未患骨关节炎的犬相比，患骨关节炎犬的滑液中维生素E浓度升高的研究。
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