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睡眠模式预测因下背痛诊断导致的残疾抚恤金:一项对芬兰双胞胎的 23 年纵向研究。

Sleep patterns as predictors for disability pension due to low back diagnoses: a 23-year longitudinal study of Finnish twins.

机构信息

School of Medicine, University of Eastern Finland, Kuopio, Finland.

出版信息

Sleep. 2013 Jun 1;36(6):891-7. doi: 10.5665/sleep.2718.

Abstract

STUDY OBJECTIVES

Impaired sleep patterns are known to be associated with many chronic conditions and ultimately they may lead to permanent work incapacity. Less is known about the associations between sleep patterns and cause-specific disability pensions, such as low back diagnoses, or whether familial factors (genetics and family environment) can affect the associations. The objective of this study was to investigate sleep patterns as predictors of disability pension due to low back diagnoses with a 23-year follow-up.

DESIGN AND SETTING

A prospective cohort study with comprehensive mailed questionnaires about sleep patterns, e.g., quality and length of sleep in 1975 and 1981. Follow-up from the national disability pension register data until 2004.

INTERVENTIONS

Not applicable.

PARTICIPANTS

There were 18,979 individuals (7,722 complete twin pairs) born before 1958.

MEASUREMENTS AND RESULTS

Cox proportional hazards regression was used to calculate hazard ratios (HR) with 95% confidence intervals (95% CI). Disability pension due to low back diagnoses had been granted to 467 individuals during the follow-up. Sleeping moderately well (HR 1.25; 95% CI 1.02, 1.53), or fairly poorly/poorly (HR 2.05; 95% CI 1.53, 2.73) at baseline predicted a significantly higher risk for disability pension. Stable patterns of sleeping either fairly well (HR 1.29; 95% CI 1.01, 1.64), or stably fairly poorly/poorly (HR 2.29; 95% CI 1.49, 3.52) between 1975 and 1981 were associated with a higher risk as compared to a stable pattern of sleeping well. Furthermore, a decrease in quality of sleep from 1975 to 1981 was associated (HR 1.34; 95% CI 1.03, 1.76) with an increased risk of disability pension.

CONCLUSIONS

Sleep quality and changes in sleep quality appear to be early predictors for disability pension due to low back diagnoses independently from other confounding factors.

摘要

研究目的

众所周知,睡眠模式的紊乱与许多慢性疾病有关,最终可能导致永久性工作能力丧失。睡眠模式与特定疾病的残疾抚恤金之间的关联,例如背部诊断,或者家族因素(遗传和家庭环境)是否会影响这些关联,了解得较少。本研究的目的是调查 23 年随访期间睡眠模式作为背部诊断导致残疾抚恤金的预测因素。

设计和设置

这是一项前瞻性队列研究,1975 年和 1981 年通过全面的邮寄问卷调查睡眠模式,例如睡眠质量和时长。随访至 2004 年国家残疾抚恤金登记数据。

干预措施

不适用。

参与者

有 18979 人(7722 对完整双胞胎)出生于 1958 年之前。

测量和结果

使用 Cox 比例风险回归计算风险比(HR)及其 95%置信区间(95%CI)。在随访期间,有 467 人因背部诊断而获得残疾抚恤金。基线时睡眠状况中等(HR1.25;95%CI1.02,1.53)或较差/差(HR2.05;95%CI1.53,2.73)预示着残疾抚恤金的风险显著增加。1975 年至 1981 年间,睡眠状况稳定,无论良好(HR1.29;95%CI1.01,1.64)或稳定较差/差(HR2.29;95%CI1.49,3.52)的模式与稳定良好的睡眠模式相比,风险更高。此外,1975 年至 1981 年期间睡眠质量下降(HR1.34;95%CI1.03,1.76)与残疾抚恤金风险增加相关。

结论

睡眠质量和睡眠质量的变化似乎是背部诊断导致残疾抚恤金的早期预测因素,独立于其他混杂因素。

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