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抗C抗体所致抗Rh溶血病:仅检测抗D抗体是否足够?

Anti Rh Hemolytic Disease due to Anti C Antibody: Is Testing for Anti D Antibodies Enough?

作者信息

Negi Gita, Singh Gaur Dushyant

机构信息

Department of Pathology, Himalayan Institute of Medical Sciences, Jolly Grant, Doiwala, Dehradun, Uttarakhand India.

出版信息

Indian J Hematol Blood Transfus. 2012 Jun;28(2):121-2. doi: 10.1007/s12288-011-0105-z. Epub 2011 Aug 28.

Abstract

Rh blood group system is a complex blood group system. Rh antibodies are produced in Rh negative individuals following exposure to foreign RBCs after transfusion or pregnancy. Anti C is a rare cause of hemolytic disease of newborn and is very scarcely reported in the literature. The aim of the present case report of Hemolytic disease caused by Anti C antibody is to bring out the fact that antibodies other than anti D should be considered in cases that give a suggestive history but no evidence of Anti D.

摘要

Rh血型系统是一个复杂的血型系统。Rh抗体在Rh阴性个体输血或妊娠后接触外来红细胞后产生。抗C是新生儿溶血病的罕见病因,文献中报道极少。本例由抗C抗体引起的溶血病病例报告的目的是揭示一个事实,即在有提示性病史但无抗D证据的病例中,应考虑除抗D以外的抗体。

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Severe neonatal hemolysis due to a maternal antibody to the low-frequency Rh antigen C(w).
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Anti-C(w) alloimmunization presenting as hydrops fetalis.表现为胎儿水肿的抗 - C(w)同种免疫
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Non-anti-D antibodies in red-cell alloimmunization.红细胞同种免疫中的非抗-D抗体。
Eur J Obstet Gynecol Reprod Biol. 2000 Sep;92(1):75-81. doi: 10.1016/s0301-2115(00)00428-0.
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Anti-C haemolytic disease requiring intrauterine and exchange transfusion.
Med J Aust. 1981 Sep 19;2(6):296. doi: 10.5694/j.1326-5377.1981.tb128325.x.

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