• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[用人血浆纤连蛋白滴眼液治疗持续性角膜上皮病变]

[Treatment of persistent corneal epithelial disorders with human plasma fibronectin eyedrops].

作者信息

Qu X A

机构信息

Beijing Institute of Ophthalmology.

出版信息

Zhonghua Yan Ke Za Zhi. 1990 Jan;26(1):21-3.

PMID:2373030
Abstract

Fibronectin (FN), a glycoprotein present in plasma and the extracellular matrix, is responsible for cellular adhesion. 14 eyes with persistent corneal epithelial defects of various etiology were treated with FN to evaluate its effect on corneal epithelial wound healing. Human plasma fibronectin eyedrops (200 micrograms/ml) were instilled 5 times in addition to gentamycin eyedrops 2 times a day. The eyes healed completely in an average 20.4 days, with no recurrence in follow-ups of 1 to 3 months.

摘要

纤连蛋白(FN)是一种存在于血浆和细胞外基质中的糖蛋白,负责细胞黏附。对14只因各种病因导致持续性角膜上皮缺损的眼睛使用纤连蛋白进行治疗,以评估其对角膜上皮伤口愈合的影响。除每天滴注2次庆大霉素眼药水外,还滴注5次人血浆纤连蛋白眼药水(200微克/毫升)。这些眼睛平均在20.4天内完全愈合,在1至3个月的随访中无复发。

相似文献

1
[Treatment of persistent corneal epithelial disorders with human plasma fibronectin eyedrops].[用人血浆纤连蛋白滴眼液治疗持续性角膜上皮病变]
Zhonghua Yan Ke Za Zhi. 1990 Jan;26(1):21-3.
2
Clinical evaluation of fibronectin eyedrops on epithelial disorders after herpetic keratitis.纤连蛋白滴眼液对疱疹性角膜炎后上皮病变的临床评估
Ophthalmology. 1985 Feb;92(2):213-6. doi: 10.1016/s0161-6420(85)34050-2.
3
Topical fibronectin therapy of persistent corneal epithelial defects. Fibronectin Study Group.局部应用纤连蛋白治疗持续性角膜上皮缺损。纤连蛋白研究小组。
Trans Am Ophthalmol Soc. 1993;91:367-86; discussion 386-90.
4
Clinical efficacy of topical homologous fibronectin in persistent corneal epithelial disorders.
Korean J Ophthalmol. 1992 Jun;6(1):12-8. doi: 10.3341/kjo.1992.6.1.12.
5
[The cornea: stasis and dynamics].[角膜:静止与动态]
Nippon Ganka Gakkai Zasshi. 2008 Mar;112(3):179-212; discussion 213.
6
Rapid preparation of purified autologous fibronectin eyedrops from patient's plasma.从患者血浆中快速制备纯化的自体纤连蛋白眼药水。
Jpn J Ophthalmol. 1982;26(4):416-24.
7
Topical fibronectin in the treatment of persistent corneal epithelial defects and trophic ulcers.
Am J Ophthalmol. 1987 Nov 15;104(5):494-501. doi: 10.1016/s0002-9394(14)74107-8.
8
Topical fibronectin treatment in persistent corneal epithelial defects and corneal ulcers.
Korean J Ophthalmol. 1990 Jun;4(1):5-11. doi: 10.3341/kjo.1990.4.1.5.
9
Persistent epithelial defect following penetrating keratoplasty: an adverse effect of diclofenac eyedrops.穿透性角膜移植术后持续性上皮缺损:双氯芬酸钠滴眼液的不良反应。
Cornea. 1995 Nov;14(6):623-7.
10
Open clinical study of eye-drops containing tetrapeptides derived from substance P and insulin-like growth factor-1 for treatment of persistent corneal epithelial defects associated with neurotrophic keratopathy.含P物质衍生四肽和胰岛素样生长因子-1的滴眼液治疗与神经营养性角膜病变相关的持续性角膜上皮缺损的开放性临床研究
Br J Ophthalmol. 2008 Jul;92(7):896-900. doi: 10.1136/bjo.2007.130013. Epub 2008 May 29.