Jin X Y
Beijing Institute of Ophthalmology.
Zhonghua Yan Ke Za Zhi. 1990 Jan;26(1):36-8.
Treatment of experimental HSV keratitis in rabbits with rHuIFN alpha-1 instillations was studied Clinical and scanning electron microscopic observations revealed that local application of rHuIFN alpha-1 protected the target cells against virus invasion and restrained development of HSV keratitis. The initial punctate lesions did not expand uniformly but linearly to form dendritic patterns due to varying sensitivity of cells to virus.
用重组人α-1干扰素滴眼剂治疗兔实验性单纯疱疹病毒性角膜炎的研究。临床和扫描电子显微镜观察显示，局部应用重组人α-1干扰素可保护靶细胞免受病毒侵袭，并抑制单纯疱疹病毒性角膜炎的发展。由于细胞对病毒的敏感性不同，最初的点状病变并非均匀扩展，而是呈线性扩展形成树枝状形态。
