Jin X Y
Beijing Institute of Ophthalmology.
Zhonghua Yan Ke Za Zhi. 1992 May;28(3):134-7.
A double blind clinical investigation on the treatment of 100 cases of HSV keratitis with rHuIFN alpha-1 and acyclovir instillations was carried out in 8 institutions in Beijing and elsewhere. Both eyedrops proved about equally effective with cure rates of 88.1% and 82.9% respectively. Until recently, 128 cumulative cases of various types of HSV keratitis treated with rHuIFN alpha-1 demonstrated a cure rate of 82.0%, indicating that topical rHuIFN alpha-1 was an effective nonspecific remedy for HSV keratitis.
在北京及其他地区的8家机构对100例单纯疱疹病毒性角膜炎患者进行了一项关于重组人α-1干扰素和阿昔洛韦滴眼剂治疗的双盲临床研究。两种滴眼剂的疗效大致相同，治愈率分别为88.1%和82.9%。截至目前，用重组人α-1干扰素治疗的128例各类单纯疱疹病毒性角膜炎累计病例的治愈率为82.0%，表明局部应用重组人α-1干扰素是治疗单纯疱疹病毒性角膜炎的一种有效的非特异性疗法。
