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General background.一般背景。
WHO Reg Publ Eur Ser. 1993;45:5-22.
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Promoting rational prescribing: an international perspective.促进合理用药:国际视角
Br J Clin Pharmacol. 1995 Jan;39(1):1-6. doi: 10.1111/j.1365-2125.1995.tb04402.x.

某三级甲等医院心血管急症药物使用趋势的研究。

A study on the drug utilization trends in the cardiovascular emergencies in a tertiary care hospital.

作者信息

Pendhari Shabbir Rafiq, Chaudhari Devendra Ramesh, Burute Shreyas Ramchandra, Bite Bapurao Motiram

机构信息

Tutor, Department of Pharmacology, Bharati Vidyapeeth University, Medical College and Hospital , sangli, Maharashtra, India .

出版信息

J Clin Diagn Res. 2013 Apr;7(4):666-70. doi: 10.7860/JCDR/2013/5277.2877. Epub 2013 Feb 20.

DOI:10.7860/JCDR/2013/5277.2877
PMID:23730642
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3644440/
Abstract

OBJECTIVES

To observe the cardiovascular emergencies which were most frequently treated and to quantify the drug utilization trends in the cardiovascular emergencies, in terms of the Defined Daily Doses [DDD] and the prescribing prevalence in the cardiovascular emergencies.

METHODS

This prescription based study was undertaken in the Medicine ICU of the government medical hospital. The age, sex, diagnosis (only cardiovascular) and the drugs which were prescribed, were recorded for each patient. Also, the brand names and the generic names of the prescribed drugs were noted. The collected data was analyzed to study the drug utilization trends.

RESULTS

It was observed that the most commonly treated cardiovascular disease was IHD. The IHD was more in males than in females who were below 50 years of age and it was nearly equal in the age groups which were above 50 years. The use of Angiotensin Converting Enzyme (ACE) inhibitors was higher than that of the beta blockers and the calcium channel blockers. The patients with cardiovascular emergencies also had preceding associated diseases like diabetes mellitus and hypertension.

CONCLUSIONS

The protocol of the management which was followed by the college in the treatment of cardiovascular emergencies was competent enough, as the clinical outcomes of the patients were favourable. But there was a guideline incongruent prescribing behaviour which was statistically significant, for which there is a need to undertake large scale studies.

摘要

目的

观察最常治疗的心血管急症,并根据限定日剂量(DDD)和心血管急症中的处方流行率,量化心血管急症中的药物使用趋势。

方法

这项基于处方的研究在政府公立医院的内科重症监护病房进行。记录每位患者的年龄、性别、诊断(仅限心血管疾病)和所开药物。还记录了所开药物的品牌名称和通用名称。对收集的数据进行分析以研究药物使用趋势。

结果

观察到最常治疗的心血管疾病是缺血性心脏病(IHD)。50岁以下男性的缺血性心脏病比女性多,50岁以上年龄组中两者几乎相等。血管紧张素转换酶(ACE)抑制剂的使用高于β受体阻滞剂和钙通道阻滞剂。心血管急症患者还患有糖尿病和高血压等先前相关疾病。

结论

该学院在治疗心血管急症时遵循的管理方案足够有效,因为患者的临床结果良好。但存在具有统计学意义的指南不一致处方行为,为此需要进行大规模研究。