Stanko P, Kruzliak P, Labas P
Department of Stomatology and Maxillofocal Surgery, Comenius University and St. Elizabeth Hospital.
Bratisl Lek Listy. 2013;114(6):345-8. doi: 10.4149/bll_2013_074.
Head and neck squamous cell carcinoma and especially oropharyngeal squamous cell carcinoma is a very significant cause of morbidity and mortality. The majors risk factors of these tumors are tobacco smoking, chewing and alcohol consumption. But there is a group, non-drinking and non-smoking, patients with oropharyngeal squamous cell carcinoma. In these patients may be oral-genital contact and human papillomavirus infection the major risk factor for oral carcinogenesis. Aim of this review is to point out this fact in correlation with clinical studies and clinical conclusion for medical practice (Fig. 1, Ref. 32).
头颈部鳞状细胞癌，尤其是口咽鳞状细胞癌，是发病和死亡的一个非常重要的原因。这些肿瘤的主要危险因素是吸烟、咀嚼烟草和饮酒。但有一群不饮酒且不吸烟的口咽鳞状细胞癌患者。在这些患者中，口交接触和人乳头瘤病毒感染可能是口腔致癌的主要危险因素。本综述的目的是结合临床研究指出这一事实，并得出对医疗实践的临床结论（图1，参考文献32）。
