Dept of Psychiatry, University of Toronto, Toronto, ON, Canada.
Best Pract Res Clin Endocrinol Metab. 2013 Apr;27(2):139-46. doi: 10.1016/j.beem.2013.04.004. Epub 2013 May 10.
An important association exists between obesity and mental illness that impacts all aspects of an individual's quality of life. This association can begin early in the developmental trajectory and we do not yet completely understand all the mechanisms linking obesity and mental illness. What we e do know is that physical health factors that often occur secondary to obesity, combined with societal attitudes toward those that are obese coupled with iatrogenic treatment factors linked to psychiatric pharmacotherapy and a number of biologic mediators result in an important and increasing common comorbidity. Recognizing this association is essential for the proper management of both conditions. The following review addresses this issue and provides clinical pearls to help deal with this issue.
肥胖症和精神疾病之间存在着重要的关联，影响着个体生活质量的各个方面。这种关联可能在个体的发育轨迹早期就开始了，而我们尚未完全理解肥胖症和精神疾病之间所有的关联机制。我们所知道的是，肥胖症常继发于一些身体健康因素，再加上社会对肥胖者的态度，以及与精神药理学治疗相关的医源性治疗因素和许多生物学介质，导致了一种重要且日益常见的共病现象。认识到这种关联对于这两种疾病的正确管理至关重要。以下综述探讨了这个问题，并提供了一些临床要点来帮助处理这个问题。
