人类在高海拔暴露后，肌肉脂褐素含量和卫星细胞体积会增加。
Muscle lipofuscin content and satellite cell volume is increased after high altitude exposure in humans.
作者信息
Martinelli M, Winterhalder R, Cerretelli P, Howald H, Hoppeler H
机构信息
Department of Anatomy University of Bern, Switzerland.
出版信息
Experientia. 1990 Jul 15;46(7):672-6. doi: 10.1007/BF01939930.
Muscle ultrastructural changes during a typical expedition to the Himalayas were analyzed by taking muscle biopsies from seven climbers before and after their sojourn at high altitude (over 5000 m for 8 weeks). M. vastus lateralis samples were analyzed morphometrically from electron micrographs. A quantitative evaluation was made of lipofuscin, satellite cells and myonuclei. Significant increases of the volume densities of lipofuscin (+ 235%) and satellite cells (+ 215%) were observed.
通过对7名登山者在喜马拉雅山进行典型探险期间的肌肉活检进行分析，这些登山者在高海拔地区（海拔超过5000米，为期8周）停留前后，采集了股外侧肌样本，从电子显微照片上进行形态计量学分析。对脂褐素、卫星细胞和肌核进行了定量评估。观察到脂褐素（增加235%）和卫星细胞（增加215%）的体积密度显著增加。
Zotero 插件