Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, UK.
Prev Med. 2013 Sep;57(3):201-5. doi: 10.1016/j.ypmed.2013.05.022. Epub 2013 May 31.
The study aims to test the hypothesis that physical activity (PA) and cardiorespiratory fitness (CRF) are associated with cardiometabolic risk factors; and to test the hypothesis that CRF modifies (changes the direction and/or strength of) the associations between PA and cardiometabolic risk factors.
PA and CRF were objectively measured in the 2008 Health Survey for England and the present study included 536 adults who completed at least 4 min of the eight-minute sub-maximal step test and wore an accelerometer for at least 10 h on at least four days. Linear regression models were fitted to examine the relationship between PA and cardiometabolic risk factors and between CRF and cardiometabolic risk factors. A test of interaction was performed to examine whether CRF modifies the associations between PA and cardiometabolic risk factors.
PA and CRF were associated with HDL cholesterol, the ratio of total to HDL cholesterol, glycated haemoglobin and BMI after adjustment for potential confounders. There was little evidence that CRF changed the direction or strength of associations between PA and cardiometabolic risk factors.
PA and CRF are associated with cardiometabolic risk factors. A larger sample is required to determine if CRF modifies associations between PA and cardiometabolic risk factors.
本研究旨在检验以下两个假设:身体活动(PA)和心肺功能(CRF)与心血管代谢风险因素有关;以及 CRF 是否改变(改变方向和/或强度)PA 与心血管代谢风险因素之间的关联。
在 2008 年英国健康调查中对 PA 和 CRF 进行了客观测量,本研究包括 536 名至少完成 4 分钟八分钟亚最大踏步测试且至少在四天佩戴加速度计至少 10 小时的成年人。线性回归模型用于检查 PA 和心血管代谢风险因素之间以及 CRF 和心血管代谢风险因素之间的关系。进行了交互检验以检查 CRF 是否改变 PA 和心血管代谢风险因素之间的关联。
PA 和 CRF 与高密度脂蛋白胆固醇、总胆固醇与高密度脂蛋白胆固醇的比值、糖化血红蛋白和 BMI 相关,在调整了潜在混杂因素后。几乎没有证据表明 CRF 改变了 PA 和心血管代谢风险因素之间关联的方向或强度。
PA 和 CRF 与心血管代谢风险因素有关。需要更大的样本量来确定 CRF 是否改变 PA 和心血管代谢风险因素之间的关联。