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胆囊收缩素、促胰液素、胰多肽与胆囊动力学及胃肠消化间期运动的关系。

Cholecystokinin, secretin, pancreatic polypeptide in relation to gallbladder dynamics and gastrointestinal interdigestive motility.

作者信息

Qvist N, Oster-Jørgensen E, Rasmussen L, Pedersen S A, Olsen O, Cantor P, Schaffalitzky de Muckadell O B

机构信息

Department of Surgical and Medical Gastroenterology, Odense University Hospital, Denmark.

出版信息

Digestion. 1990;45(3):130-7. doi: 10.1159/000200234.

DOI:10.1159/000200234
PMID:2373268
Abstract

Using a combined technique of hepatobiliary scintigraphy and gastrointestinal motility recordings, the changes in blood concentrations of cholecystokinin (CCK), secretin and pancreatic polypeptide (PP) were studied in relation to gastrointestinal motility and gallbladder dynamics in the interdigestive state in 7 healthy male volunteers. No changes in CCK concentration were found in relation to the migrating motor complex (MMC). In 3 subjects a slightly but insignificant elevated secretin level was seen during phase I of the MMC, otherwise no changes were observed. More pronounced fluctuations in PP appeared with significantly higher values during phase III compared to phase II. Values of concentrations of CCK, secretin and PP in periods with gallbladder filling were not significantly different from the values in periods of emptying.

摘要

采用肝胆闪烁显像和胃肠动力记录相结合的技术,对7名健康男性志愿者在消化间期的胃肠动力和胆囊动力学相关的胆囊收缩素(CCK)、促胰液素和胰多肽(PP)血浓度变化进行了研究。未发现CCK浓度与移行性运动复合波(MMC)有关的变化。在3名受试者中,MMC的I期促胰液素水平略有升高但不显著,其他情况下未观察到变化。与II期相比,III期PP出现更明显的波动,且值显著更高。胆囊充盈期CCK、促胰液素和PP的浓度值与排空期的值无显著差异。

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