非侵入性脑刺激在人类视觉系统研究中的应用。
Noninvasive brain stimulation in the study of the human visual system.
机构信息
Department of Neurology, Bereson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Boston, MA, USA.
出版信息
J Glaucoma. 2013 Jun-Jul;22 Suppl 5(0 5):S39-41. doi: 10.1097/IJG.0b013e3182934b31.
Abstract
There are currently two techniques to manipulate brain function non-invasively: transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). These brain stimulation techniques work to cause long-term change within the brain. We have been combining noninvasive brain stimulation with functional magnetic resonance imaging (fMRI) to investigate the plasticity of brain networks. When fMRI is used as an outcome measure, it is possible to identify the specificity of tDCS-modulated plasticity in a visual rehabilitation protocol. Alternatively, fMRI can be used as a guide for stimulation. Brain stimulation with TMS affects neural networks, and fMRI guidance combined with an understanding of network effects of TMS may improve TMS therapy.
摘要
目前有两种非侵入性大脑功能操作技术
经颅磁刺激（TMS）和经颅直流电刺激（tDCS）。这些大脑刺激技术旨在引起大脑内的长期变化。我们一直在将非侵入性脑刺激与功能磁共振成像（fMRI）结合起来，以研究大脑网络的可塑性。当 fMRI 用作结果测量时，可以确定在视觉康复方案中 tDCS 调节的可塑性的特异性。或者，fMRI 可以用作刺激的指南。TMS 的脑刺激会影响神经网络，而将 fMRI 指导与对 TMS 网络效应的理解相结合，可能会改善 TMS 治疗。
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