Berenson-Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, KS-158 Boston, Massachusetts 02215, USA.
Nat Rev Neurosci. 2010 Jan;11(1):44-52. doi: 10.1038/nrn2758. Epub 2009 Nov 25.
There is growing evidence that sensory deprivation is associated with crossmodal neuroplastic changes in the brain. After visual or auditory deprivation, brain areas that are normally associated with the lost sense are recruited by spared sensory modalities. These changes underlie adaptive and compensatory behaviours in blind and deaf individuals. Although there are differences between these populations owing to the nature of the deprived sensory modality, there seem to be common principles regarding how the brain copes with sensory loss and the factors that influence neuroplastic changes. Here, we discuss crossmodal neuroplasticity with regards to behavioural adaptation after sensory deprivation and highlight the possibility of maladaptive consequences within the context of rehabilitation.
越来越多的证据表明，感官剥夺与大脑中的跨模态神经可塑性变化有关。在视觉或听觉剥夺后，与丧失的感觉相关的大脑区域被保留的感觉模态所招募。这些变化是盲人或聋人适应和补偿行为的基础。尽管由于剥夺感觉模态的性质，这些人群之间存在差异，但似乎存在一些关于大脑如何应对感觉丧失和影响神经可塑性变化的因素的共同原则。在这里，我们讨论了感官剥夺后行为适应方面的跨模态神经可塑性，并强调了在康复背景下可能出现的适应不良后果。
