Department of Obstetrics and Gynecology, Strasbourg University Teaching Hospital, Strasbourg, France.
Prenat Diagn. 2013 Sep;33(9):894-8. doi: 10.1002/pd.4158. Epub 2013 Jun 7.
This study aims to evaluate the utility of first trimester cervical ultrasonography in predicting preterm delivery by separate analysis of measurements of cervical and isthmus length.
This is a cohort study based on data collected prospectively on singletons between 1 July 2011 and 1 February 2013. Mean cervical, isthmus and cervico-isthmic complex length were measured for deliveries before and after 37 weeks.
A total of 1494 pregnancies were analysed, including 51 cases of spontaneous preterm delivery (3.4%). The cervico-isthmic complex in the first trimester was significantly shorter in patients who delivered before term (43.8 mm vs 47.5 mm, p = 0.04). This difference is related to differences in length at the isthmus (10.7 mm vs 14.1 mm, p = 0.005) rather than at the cervix proper (34.5 mm vs 35.0 mm, p = 0.56).
Measurement of the cervico-isthmic complex enables detection of a number of patients who will go on to deliver before term. Further studies are necessary to confirm that isthmic length and not cervical length is predictive of preterm delivery.
本研究旨在通过分别分析宫颈和峡部长度来评估早孕期宫颈超声在预测早产中的作用。
这是一项基于 2011 年 7 月 1 日至 2013 年 2 月 1 日期间收集的单胎数据的队列研究。测量了 37 周前和后分娩的宫颈、峡部和宫颈峡部复合体的平均长度。
共分析了 1494 例妊娠，其中 51 例自发性早产（3.4%）。在早产患者中，早孕期宫颈峡部复合体明显缩短（43.8mm 比 47.5mm，p=0.04）。这种差异与峡部长度的差异有关（10.7mm 比 14.1mm，p=0.005），而不是宫颈本身的长度差异（34.5mm 比 35.0mm，p=0.56）。
宫颈峡部复合体的测量可检测到许多将提前分娩的患者。需要进一步的研究来证实峡部长度而不是宫颈长度可以预测早产。
