Immunization Program, Oregon Health Authority, Portland, OR, USA.
Pediatrics. 2013 Jul;132(1):44-8. doi: 10.1542/peds.2012-3866. Epub 2013 Jun 3.
Giving recommended immunizations during sick visits for minor and acute illness such as acute otitis media has long been an American Academy of Pediatrics/Advisory Committee on Immunization Practice recommendation. An addition to the American Academy of Pediatrics policy in 2010 advised considering whether giving immunizations at the sick visit would discourage making up missed well-baby visits. This study quantifies the potential tradeoff between sick-visit immunizations and well-baby visits.
This study was a retrospective cohort analysis with a case-control component of sick visits for acute otitis media that supplanted normal well-baby visits at age 2, 4, or 6 months. Infants were stratified for sick-visit immunization, no sick-visit immunization but quick makeup well-baby visits, or no sick-visit immunizations or quick makeup visits. Immunization rates and well-baby visit rates were assessed through 24 months of age.
For 1060 study cases, no significant difference was detected in immunization rates or well-baby visits through 24 months of age between those with or without sick-visit immunizations. Thirty-nine percent of infants without a sick-visit shot failed to return for a quick makeup well-baby visit; this delayed group was significantly less likely to be up-to-date for immunizations (relative risk: 0.66) and had fewer well-baby visits (mean: 3.8) from 2 through 24 months of age compared with those with sick-visit shots (mean: 4.7).
The substantial risk that infants will not return for a timely makeup well-baby visit after a sick visit should be included in any consideration of whether to delay immunizations.
在为小儿和急性疾病(如急性中耳炎)就诊时提供推荐的免疫接种,长期以来一直是美国儿科学会/免疫实践咨询委员会的建议。2010 年,美国儿科学会的政策增加了一项建议,即考虑在就诊时接种疫苗是否会阻碍错过的常规婴儿就诊。本研究量化了在就诊时接种疫苗与常规婴儿就诊之间的潜在权衡。
这是一项回顾性队列分析,对替代 2、4 或 6 个月龄正常常规婴儿就诊的急性中耳炎就诊进行病例对照研究。根据就诊时是否接种疫苗、未接种疫苗但及时进行常规婴儿就诊或既未接种疫苗也未及时进行常规婴儿就诊,对婴儿进行分层。通过 24 个月龄评估疫苗接种率和常规婴儿就诊率。
在 1060 例研究病例中,有或没有就诊时接种疫苗的婴儿在 24 个月龄时的疫苗接种率或常规婴儿就诊率均无显著差异。39%的未就诊时接种疫苗的婴儿未能及时进行常规婴儿就诊;与就诊时接种疫苗的婴儿相比,该延迟组的疫苗接种率明显较低(相对风险:0.66),且从 2 个月龄到 24 个月龄的常规婴儿就诊次数较少(平均:3.8 次)。
在考虑是否推迟免疫接种时,应考虑到婴儿在就诊后及时进行常规婴儿就诊的可能性很大。