Fiks Alexander G, Hunter Kenya F, Localio A Russell, Grundmeier Robert W, Alessandrini Evaline A
Pediatric Research Consortium, Children's Hospital of Philadelphia, 3535 Market St, Philadelphia, PA 19104, USA.
Pediatrics. 2008 May;121(5):898-905. doi: 10.1542/peds.2007-2174.
We assessed the impact of immunization at sick visits on subsequent and overall well-child care.
We performed a retrospective cohort study using electronic health record data from 4 urban practices affiliated with an academic medical center. Participants included all children born between September 1, 2003, and July 31, 2004, with a visit at a study practice before 6 weeks of age and > or = 1 sick visit (n = 1675). The main outcome measures were (1) attendance at a well-child visit within 60 days after an index sick visit by children due for vaccines and preventive care and (2) the overall number of well-child visits kept by children between 6 weeks and 13 months of age.
Among all demographic and health-related factors considered, immunization receipt at a sick visit was associated most strongly with decreased subsequent well-child care. Among children already delayed (late) for vaccines, 31% returned for well-child care if immunizations were given at eligible sick visits, compared with 47% of those who received no vaccines (risk difference, with adjustment for covariates: -16%). Among those without immunization delay, 42% of children who received vaccines returned for well-child care, compared with 73% of those who received no vaccines (risk difference: -31%). Although 5 well-child visits are recommended, children with no immunizations at sick visits had an adjusted predicted number of 3.8 well-child visits, those with 1 sick visit with immunizations had 3.3 visits, and those with > or = 2 sick visits with immunizations had 2.8 visits between 6 weeks and 13 months of age.
Immunization at sick visits was associated with decreased rates of well-child care, especially among those without previous vaccine delay. This strong association between immunization at sick visits and well-child care should be considered in any plan to restructure pediatric preventive care.
我们评估了患病就诊时接种疫苗对后续及整体儿童健康保健的影响。
我们利用来自一家学术医疗中心附属的4家城市医疗机构的电子健康记录数据进行了一项回顾性队列研究。参与者包括2003年9月1日至2004年7月31日期间出生、在6周龄前到研究医疗机构就诊且有≥1次患病就诊经历的所有儿童(n = 1675)。主要结局指标为:(1)应接种疫苗和接受预防性保健的儿童在首次患病就诊后60天内进行儿童健康检查的情况;(2)6周龄至13月龄儿童进行儿童健康检查的总次数。
在所有考虑的人口统计学和健康相关因素中,患病就诊时接种疫苗与后续儿童健康保健减少的关联最为强烈。在疫苗接种已延迟的儿童中,如果在符合条件的患病就诊时接种疫苗,31%的儿童会返回接受儿童健康保健,而未接种疫苗的儿童这一比例为47%(风险差异,经协变量调整:-16%)。在未出现疫苗接种延迟的儿童中,接种疫苗的儿童42%返回接受儿童健康保健,而未接种疫苗的儿童这一比例为73%(风险差异:-31%)。尽管建议进行5次儿童健康检查,但患病就诊时未接种疫苗的儿童经调整后的预测儿童健康检查次数为3.8次,有1次患病就诊且接种疫苗的儿童为3.3次,有≥2次患病就诊且接种疫苗的儿童在6周龄至13月龄期间为2.8次。
患病就诊时接种疫苗与儿童健康保健率降低有关,尤其是在之前未出现疫苗接种延迟的儿童中。在任何重组儿科预防性保健的计划中,都应考虑患病就诊时接种疫苗与儿童健康保健之间的这种强烈关联。