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永久性腹腔内置管治疗复发性恶性腹水的结局。

Outcomes of permanent peritoneal ports for the management of recurrent malignant ascites.

机构信息

Department of Medical Oncology, Royal Prince Alfred Hospital, Camperdown, Australia.

出版信息

J Palliat Med. 2013 Aug;16(8):938-40. doi: 10.1089/jpm.2012.0535. Epub 2013 Jun 4.

Abstract

BACKGROUND AND OBJECTIVE

Ascites complicates many advanced malignancies, resulting in abdominal pain, discomfort, anorexia, nausea, and dyspnea. Percutaneous drainage relieves symptoms in the vast majority of patients. The aim of this study was to determine the course and outcomes in a consecutive series of patients with recurrent ascites managed with permanent peritoneal ports.

METHODS

A prospective longitudinal descriptive study from 2006 to 2011, involving patients treated at the Sydney Cancer Center (New South Wales, Australia).

RESULTS AND CONCLUSIONS

A total of 155 drainages were performed in 24 patients; 26% of drainages (n=40) in the patient's home and the remainder in the ambulatory care clinic. Grade 3 or higher adverse events occured in less than 25% of all draining procedures. An improvement in symptoms was demonstrated in almost half of all individual drainage procedures. Our findings suggest that peritoneal ports are efficacious, safe, and are associated with symptomatic relief in most patients.

摘要

背景和目的

腹水是许多晚期恶性肿瘤的并发症,会导致腹痛、不适、厌食、恶心和呼吸困难。经皮引流术可缓解绝大多数患者的症状。本研究旨在确定连续系列复发性腹水患者采用永久性腹膜端口管理的过程和结果。

方法

这是一项 2006 年至 2011 年在悉尼癌症中心(澳大利亚新南威尔士州)进行的前瞻性纵向描述性研究,涉及接受治疗的患者。

结果与结论

24 例患者共进行了 155 次引流;26%(n=40)的引流在患者家中进行,其余的在日间护理诊所进行。所有引流操作中,不到 25%的患者发生 3 级或更高级别的不良事件。几乎一半的单个引流操作都显示出症状的改善。我们的研究结果表明,腹膜端口是有效、安全的,并且在大多数患者中与症状缓解相关。

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