Pd/C-catalyzed synthesis of oxamates by oxidative cross double carbonylation of amines and alcohols under co-catalyst, base, dehydrating agent, and ligand-free conditions.

This work reports a mild, efficient, and ligand-free Pd/C-catalyzed protocol for the oxidative cross double carbonylation of amines and alcohols. Notably, the reaction does not requires any base, co-catalyst, dehydrating agent, or ligand. Pd/C solves the problem of catalyst recovery, and the catalyst was recycled up to six times.