Department of Chemistry and FQRNT Center for Green Chemistry and Catalysis, McGill University, Montreal, QC, H3A 2K6, Canada.
Org Lett. 2012 Nov 2;14(21):5606-9. doi: 10.1021/ol3027279. Epub 2012 Oct 15.
Pd-catalyzed intermolecular aerobic dehydrogenative aromatizations have been developed for the arylation of amines with nonaromatic ketones. Under optimized reaction conditions, primary and secondary amines are selectively arylated in good yields with cyclohexanones and 2-cyclohexen-1-ones in the presence of a Pd-catalyst under an atmosphere of molecular oxygen.
Pd 催化的分子间有氧脱氢芳构化已被开发用于胺与非芳酮的芳基化反应。在优化的反应条件下，在 Pd 催化剂存在下，在分子氧气氛中，伯胺和仲胺能以良好的收率选择性地与环己酮和 2-环己烯-1-酮芳基化。
